MS Treatments and Pregnancy
October 9, 2018
Many women with multiple sclerosis are diagnosed during childbearing years. They ask about their risks concerning the disease during pregnancy and the risk for their children. Women with MS have uncomplicated pregnancies and deliveries from OB perspective. They worry about their chance of disease progression with new relapses during pregnancy. They wonder about stopping their disease modifying medications, (DMT ), and risk of relapse. They question whether the medication will harm their fetus....
Head Trauma and risk of Multiple Sclerosis
October 3, 2018
I have been asked by patients if their prior history of trauma brought on their MS. It was interesting to read this article on childhood head trauma and risk of subsequent diagnosis of multiple sclerosisIn this study, the authors systematically analyzed longitudinally collected data from the national Swedish registry to look for a possible association between head trauma in childhood and adolescence and risk of subsequent multiple sclerosis. This is the largest study yet that examined...
Sexual Dimorphism of the Blood Brain Barrier and its relevance to MS
September 25, 2018
MS, along with many other neurological diseases, is partially characterized by permeability of the blood-brain barrier (BBB). This barrier is comprised of blood vessels and associated cells that are responsible for tightly controlling precisely what nutrients, proteins, and other molecules are granted access to the privileged environment of the brain. While the role of the BBB in health and disease is widely accepted, we still have much to learn about how it typically protects the central...
