New study addresses the safety of intravenous methylprednisolone (IVMP) during breastfeeding.
August 6, 2018
It is well known that the risk of an MS flair increases dramatically in the post-partum period. As a consequence, women with MS who have recently given birth are faced with the difficult question of should they continue breast feeding while taking steroids (methylprednisolone is a glucocorticoid, a type of steroid) or should they stop breast feeding. There has been little scientific guidance on this subject in the past leaving women in the difficult position of deciding on their own as to the...
Potential new medication for progressive MS shows promise in early trial
July 25, 2018
While the treatment armamentarium for MS has vastly expanded in the last decade and continues to grow, these treatments have been predominantly for the relapsing forms of the disease, and effective treatments for progressive MS remain a glaring need.Ibudilast (MN-166, MediciNova) is a phosphodiesterase inhibitor with anti-inflammatory properties and potentially neuroprotective activity as well, which was tested in a Phase 2 trial of progressive MS patients.Ibudilast has been marketed in Japan...
Exploring mechanisms of disease progression
July 25, 2018
Dr. Susan Gauthier’s research passion lies in uncovering the underlying principles that govern disease progression in Multiple Sclerosis (MS). Despite potent anti-inflammatory treatment and other strides in MS, predicting a patient’s disease progression still eludes us. Furthermore, there has been very little impact on altering the clinical course of MS once patients enter the progressive phase.Her research focuses on exploring two main hypotheses on why people may progress:Years of loss of...
