Anti-CD20 Therapies for African American Vs Caucasian Americans with Relapsing MS
June 9, 2023
We did a study to examine the efficacy of all B cell targeted therapies ( ocrelizumab, rituximab, ofatumumab) on AfricanAmerican MS (AAMS) patients and Caucasian American MS (CAMS) patients.I did this study under the mentorship of Dr Jai Perumal.
MOG Antibody-Associated Disease ( MOGAD)
May 10, 2023
Myelin Oligodendrocyte glycoprotein ( MOG) antibody associated disease is now being recognized as an unique entity different from multiple sclerosis and Neuromyelitis opticaIt is also a central nervous system inflammatory disease like MS and NMOIt is defined by high titers of serum MOG-AbCan have a monophasic or relapsing course.About 50 % of the time it is monophasic.Persistent high serum titers of MOG-ab increases the likelihood of having relapses.Characterized more commonly by presentation...
Menopause, cognition, and MS
April 5, 2023
The proportion of female MS patients who will go through menopause constitue a significant number. Cognitive disturbances such as brain fog, lack of focus as well as memory loss are some of the most common complaints during the menopausal period with a high prevalence which impacts personal life and work of even healthy women.A recent paper underscores that cognitive decline is greater in older MS patients compared to older healthy individuals, providing evidence that the combination of aging...
